Preliminary assessment of anti-α-Gal IgG and IgM levels in patients with patent Plasmodium vivax infection
Mem. Inst. Oswaldo Cruz
; 114: e190145, 2019. tab, graf
Article
en En
| LILACS
| ID: biblio-1040609
Biblioteca responsable:
BR1.1
ABSTRACT
Anti-α-Gal responses may exert a protective effect in falciparum malaria. However, the biological role of such antibodies is still unknown during Plasmodium vivax infections. We investigated IgG and IgM responses to α-Gal in individuals with vivax malaria. Anti-α-Gal IgG and IgM levels were higher in these patients than in controls, but no significant correlation was found between parasitaemia and anti-α-Gal response, nor between this response and ABO blood group status. This is the first study to investigate anti-α-Gal antibodies in P. vivax-infected patients; a larger survey is necessary to achieve a better understanding of host immune response during vivax malaria.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
LILACS
Asunto principal:
Plasmodium vivax
/
Inmunoglobulina G
/
Inmunoglobulina M
/
Anticuerpos Antiidiotipos
/
Malaria Vivax
Límite:
Adult
/
Humans
Idioma:
En
Revista:
Mem. Inst. Oswaldo Cruz
Asunto de la revista:
MEDICINA TROPICAL
/
PARASITOLOGIA
Año:
2019
Tipo del documento:
Article
País de afiliación:
Brasil
/
Estados Unidos