Brazilian Sepsis Epidemiological Study (BASES study)
Critical Care
; 8(4): 251-260, 2004 08 04. tab
Artículo
en Inglés
| Sec. Est. Saúde SP, SESSP-IDPCPROD, Sec. Est. Saúde SP
| ID: biblio-1062291
Biblioteca responsable:
BR79.1
Ubicación: BR79.1
ABSTRACT
(ICUs), including Brazil, are lacking. This study was designed to verify the actual incidence density and outcome of sepsis in Brazilian ICUs. We also assessed the association between the Consensus Conference criteria and outcome Methods This is a multicenter observational cohort study performed in five private and public, mixed ICUs from two different regions of Brazil. We prospectively followed 1383 adult patients consecutively admitted to those ICUs from May 2001 to January 2002, until their discharge, 28th day of stay, or death. For all patients we collected the following data at ICU admission age, gender, hospital and ICU admission diagnosis, APACHE II score, and associated underlying diseases. During the following days, we looked for systemic inflammatory response syndrome (SIRS), sepsis, severe sepsis, and septic shock criteria, as well as recording the sequential organ failure assessment score.Infection was diagnosed according to CDC criteria for nosocomial infection, and for community-acquired infection, clinical, radiological and microbiological parameters were used. Results For the whole cohort, median age was 65.2 years (4976), median length of stay was 2 days (16), and the overall 28-day mortality rate was 21.8%. Considering 1383 patients, the incidence density rates for sepsis, severe sepsis and septic shock were 61.4, 35.6 and 30.0 per 1000 patient-days, respectively. The mortality rate of patients with SIRS, sepsis, severe sepsis and septic shock increased progressively from 24.3% to 34.7%, 47.3% and 52.2%, respectively. For patients with SIRS without infection the mortality rate was 11.3%. The main source of infection was lung/respiratory tract. Conclusion Our preliminary data suggest that sepsis is a major public health problem in Brazilian ICUs, with an incidence density about 57 per 1000 patient-days. Moreover, there was a close association between ACCP/SCCM categories and mortality rate.
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Colección:
Bases de datos nacionales
/
Brasil
Contexto en salud:
ODS3 - Salud y Bienestar
/
ODS3 - Meta 3.3 Poner fin a las enfermedades desatendidas y detener enfermedades transmisibles
Problema de salud:
Meta 3.3: Poner fin a las enfermedades desatendidas y detener enfermedades transmisibles
/
Sepsis
Base de datos:
Sec. Est. Saúde SP
/
SESSP-IDPCPROD
Asunto principal:
Asepsia
/
Epidemiología
/
Incidencia
Tipo de estudio:
Ensayo clínico controlado
/
Estudio de incidencia
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Estudio observacional
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Estudio pronóstico
/
Factores de riesgo
País/Región como asunto:
America del Sur
/
Brasil
Idioma:
Inglés
Revista:
Critical Care
Año:
2004
Tipo del documento:
Artículo
Institución/País de afiliación:
Hospital Israelita Albert Einstein/BR
/
Hospital dos Servidores do Estado São Paulo/BR
/
Instituto Dante Pazzanese de Cardiologia/BR
/
Universidade Ferderal de Santa Catarina/BR
/
Universidade de Santo Amaro/BR