Serial assessment of arterial structure and function in patients with coarctation of the aorta undergoing stenting
Int J Cardiovasc Imaging
; 32(5): 729-739, 2016.
Artículo
en Inglés
| Sec. Est. Saúde SP, SESSP-IDPCPROD, Sec. Est. Saúde SP
| ID: biblio-1063481
Biblioteca responsable:
BR79.1
Ubicación: BR79.1
ABSTRACT
Stenting for CoA has become an acceptable treatment modality in the last 20 years. However little is known about arterial changes after this procedure. To assess arterial structure and function including peripheral reactivity and stiffness and intima-media thickness (IMT) pre and post stenting for coarctation of the aorta (CoA). Twenty-one patients [median age 15 years (8-39)] were studied at baseline, 1 day, 6 months and 1 year after stenting. Twenty-one healthy subjects (11 matched) were used as controls. Left ventricular (LV) mass, ejection fraction, flow-mediated dilation (FMD) and nitrate-mediated dilation (NMD) of left brachial artery, common carotid (CC) and right subclavian artery (RSCA) IMT and pulse wave velocity (PWV) were assessed by echocardiography and vascular ultrasound. CoA patients had higher LV indexed mass (p < 0.0001), impaired FMD (p < 0.0001) and NMD (p < 0.0001), increased PWV (p < 0.0001), carotid and RSCA IMT (both p < 0.0001). All procedures were successful and resulted in significant gradient reduction (p < 0.001). One year after stenting there was improvement in LV function (p = 0.034) and although there was significant reduction of LV mass (103.29 ± 24.77 vs...
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Colección:
Bases de datos nacionales
/
Brasil
Base de datos:
Sec. Est. Saúde SP
/
SESSP-IDPCPROD
Asunto principal:
Vasodilatación
/
Stents
/
Grosor Intima-Media Carotídeo
Idioma:
Inglés
Revista:
Int J Cardiovasc Imaging
Año:
2016
Tipo del documento:
Artículo
Institución/País de afiliación:
AC Camargo Cancer Center/BR
/
Instituto Dante Pazzanese de Cardiologia/BR