Your browser doesn't support javascript.
loading
Mast cell degranulation in periodontal disease from HIV-infected individuals
Souto, Giovanna Ribeiro; Jesus, Alessandro Oliveira de; Segundo, Takeshi Kato; Perdigão, Paôlla Freitas; Abreu, Lucas Guimarães; Costa, Fernando Oliveira; Mesquita, Ricardo Alves.
Afiliación
  • Souto, Giovanna Ribeiro; Pontifical Catholic University of Minas Gerais. Hospital Público Regional de Betim. Department of Dentistry. Belo Horizonte. BR
  • Jesus, Alessandro Oliveira de; Universidade Federal de Minas Gerais. School of Dentistry. Department of Oral Surgery and Pathology. Belo Horizonte. BR
  • Segundo, Takeshi Kato; Faculdade Arnaldo de Odontologia Belo Horizonte. Belo Horizonte. BR
  • Perdigão, Paôlla Freitas; D'OR Institute for Research and Education. Rio de Janeiro. BR
  • Abreu, Lucas Guimarães; Universidade Federal de Minas Gerais. School of Dentistry. Department of Paediatric Dentistry. Belo Horizonte. BR
  • Costa, Fernando Oliveira; Universidade Federal de Minas Gerais. School of Dentistry. Department of Oral Surgery and Pathology. Belo Horizonte. BR
  • Mesquita, Ricardo Alves; Universidade Federal de Minas Gerais. School of Dentistry. Department of Oral Surgery and Pathology. Belo Horizonte. BR
Braz. j. oral sci ; 18: e191445, jan.-dez. 2019. ilus
Article en En | LILACS, BBO | ID: biblio-1094900
Biblioteca responsable: BR218.1
ABSTRACT

Aim:

The objective was to compare the density and degranulation of mast cells on specimens obtained from individuals diagnosed with gingivitis or chronic periodontitis who were either non-HIV-infected or HIV-infected patients treated with highly active antiretroviral therapy (HAART).

Methods:

Gingival samples were taken from 16 non-HIV-infected individuals and 17 HIV-infected individuals diagnosed with gingivitis and chronic periodontitis. The samples were processed and tained with 0.3 percent o-toluidine blue. Densities (cells/mm²) and percentages of intact and degranulated mast cells were obtained.

Results:

No statistically significant differences were observed in the mast cell density and the percentage of degranulated mast cells between non-HIV-infected and HIV-infected individuals diagnosed with gingivitis and chronic periodontitis. Mononuclear inflammatory infiltrate was weakly correlated with the percentage of mast cells degranulated for both groups.

Conclusions:

There are no differences of the density and degranulation of mast cells in gingival tissue between non-HIV-infected and HIV-infected patients undergoing HAART, both groups with diagnosis of gingivitis or chronic periodontitis. This may be a result of the recovery of the immunologic system by HAART treatment.
Asunto(s)
Palabras clave

Texto completo: 1 Colección: 01-internacional Base de datos: BBO / LILACS Asunto principal: Enfermedades Periodontales / VIH / Periodontitis Crónica / Gingivitis / Mastocitos / Mucosa Bucal Límite: Female / Humans / Male Idioma: En Revista: Braz. j. oral sci Asunto de la revista: ODONTOLOGIA Año: 2019 Tipo del documento: Article País de afiliación: Brasil Pais de publicación: Brasil

Texto completo: 1 Colección: 01-internacional Base de datos: BBO / LILACS Asunto principal: Enfermedades Periodontales / VIH / Periodontitis Crónica / Gingivitis / Mastocitos / Mucosa Bucal Límite: Female / Humans / Male Idioma: En Revista: Braz. j. oral sci Asunto de la revista: ODONTOLOGIA Año: 2019 Tipo del documento: Article País de afiliación: Brasil Pais de publicación: Brasil