Prevalence of red blood cell alloimmunization in multiply transfused patients
Clin. biomed. res
; 40(2): 91-95, 2020.
Article
en En
| LILACS
| ID: biblio-1148106
Biblioteca responsable:
BR18.1
ABSTRACT
Introduction:
To analyze the prevalence of alloantibodies in multiply transfused patients.Methods:
This study was a retrospective, exploratory and descriptive study with a quantitative approach. The study sample comprised 185 patients transfused at a referral service in the city of Passo Fundo, Rio Grande do Sul, from January 2016 to February 2018.Results:
Overall, the antibodies identified were as follows anti-E in 47 patients (18%), anti-D and anti-K in 28 patients each (11%), anti-C in 21 patients (8.1%), and inconclusive antibody results in 23 patients (8.9%). Females were a majority (55.7%), mean age was 48.8 years and mean quantity of blood transfused was 7.2 bags. Cardiovascular disorders were the most common comorbidities, in 39 patients (21.2%), followed by oncological disorders, in 38 patients (18.4%).Conclusion:
Alloimmunization is an important and frequent clinical condition that increases the risk of hemolytic reactions and is associated with significant patient morbidity and mortality. (AU)Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
LILACS
Asunto principal:
Receptores de Trasplantes
/
Anticuerpos
Tipo de estudio:
Prevalence_studies
/
Risk_factors_studies
Límite:
Female
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Humans
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Male
Idioma:
En
Revista:
Clin. biomed. res
Asunto de la revista:
MEDICINA
Año:
2020
Tipo del documento:
Article
País de afiliación:
Brasil
Pais de publicación:
Brasil