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A pilot study of three potential vaccines for leprosy in Bombay
Ganapati, R; Revankar, Chandrakant R; Lockwood Diana NJ; Wilson, Rowan C; Price, Janet E; Ashton, Penelope; Ashton, Leslie; Holmes, Rowena M; Bennett, Chad; Stanford, John L; Ress, JW.
Afiliación
  • Ganapati, R; The Bombay Leprosy Project. Bombay. IN
  • Revankar, Chandrakant R; The Bombay Leprosy Project. Bombay. IN
  • Lockwood Diana NJ; University College and Middlesex School. London. GB
  • Wilson, Rowan C; University College and Middlesex School. London. GB
  • Price, Janet E; University College and Middlesex School. London. GB
  • Ashton, Penelope; University College and Middlesex School. London. GB
  • Ashton, Leslie; University College and Middlesex School. London. GB
  • Holmes, Rowena M; University College and Middlesex School. London. GB
  • Bennett, Chad; University College and Middlesex School. London. GB
  • Stanford, John L; University College and Middlesex School. London. GB
  • Ress, JW; University College and Middlesex School. London. GB
Int. j. lepr. other mycobact. dis ; 57(1): 33-37, Mar. 1989. tab
Artículo en Inglés | Sec. Est. Saúde SP, HANSEN, Hanseníase, SESSP-ILSLACERVO, Sec. Est. Saúde SP | ID: biblio-1226407
Biblioteca responsable: BR191.1
Ubicación: [{"text": "Br191.1"}]
ABSTRACT
Three vaccines, BCG Glaxo alone (vaccine A), BCG Glaxo plus 10(7) killed Mycobacterium vaccae (vaccine B), and BCG Glaxo plus 10(7) killed M. leprae (vaccine C), were given to groups of selected children. The effects of these vaccines on subsequent quadruple skin testing 1-3 years after vaccination were compared. All three vaccines equally and significantly (p less than 0.00001) increased positivity to tuberculin, but only vaccine B was found to significantly enhance development of skin-test positivity to leprosin A (p less than 0.002). The data support the evidence previously obtained in rural Iran that the combination of BCG with killed M. vaccae is likely to be a better vaccine for leprosy than is BCG alone
Asunto(s)
Texto completo: Disponible Colección: Bases de datos nacionales / Brasil Contexto en salud: Enfermedades Desatendidas Problema de salud: Lepra / Enfermedades Desatendidas Base de datos: HANSEN / Hanseníase / Sec. Est. Saúde SP / SESSP-ILSLACERVO Asunto principal: Lepra / Mycobacterium leprae Límite: Adolescente / Niño, preescolar / Humanos Idioma: Inglés Revista: Int. j. lepr. other mycobact. dis Año: 1989 Tipo del documento: Artículo Institución/País de afiliación: The Bombay Leprosy Project/IN / University College and Middlesex School/GB
Texto completo: Disponible Colección: Bases de datos nacionales / Brasil Contexto en salud: Enfermedades Desatendidas Problema de salud: Lepra / Enfermedades Desatendidas Base de datos: HANSEN / Hanseníase / Sec. Est. Saúde SP / SESSP-ILSLACERVO Asunto principal: Lepra / Mycobacterium leprae Límite: Adolescente / Niño, preescolar / Humanos Idioma: Inglés Revista: Int. j. lepr. other mycobact. dis Año: 1989 Tipo del documento: Artículo Institución/País de afiliación: The Bombay Leprosy Project/IN / University College and Middlesex School/GB
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