Small airway disease in COPD associated to biomass exposure
Rev. invest. clín
; 71(1): 70-78, Jan.-Feb. 2019. tab, graf
Artículo
en Inglés
| LILACS
| ID: biblio-1289671
Biblioteca responsable:
BR1.1
ABSTRACT
Abstract Chronic obstructive pulmonary disease (COPD) is a complex and heterogeneous entity that may result from different causative agents and risk factors and may follow diverse clinical courses, including COPD secondary to biomass smoke exposure. At present, this phenotype is becoming more important for two reasons: first, because at least almost half of the worlds population is exposed to biomass smoke, and second, because the possibility of it being diagnosed is increasing. Biomass smoke exposure COPD affects primarily women and is related with insults to the airways occurred during early life. Although constituents of biomass smoke and tobacco smoke are similar, the physiopathological changes they induce differ depending not only on the chemical composition (related with the type of fuel used) but also on the particle size and the inhalation pattern. Evidence has shown that biomass smoke exposure affects the airway, predominantly the small airways causing anthracofibrosis and peribronchiolar fibrosis changes that will clinically translate into chronic bronchitis symptoms, with a high impact on the quality of life. In this review, we focus especially on the main epidemiological and clinical differences between COPD secondary to biomass exposure and COPD caused by tobacco exposure.
Texto completo:
Disponible
Colección:
Bases de datos internacionales
Base de datos:
LILACS
Asunto principal:
Humo
/
Biomasa
/
Enfermedad Pulmonar Obstructiva Crónica
Tipo de estudio:
Estudio de etiología
/
Factores de riesgo
Aspecto:
Preferencia del paciente
Límite:
Femenino
/
Humanos
/
Masculino
Idioma:
Inglés
Revista:
Rev. invest. clín
Asunto de la revista:
Medicina
Año:
2019
Tipo del documento:
Artículo
País de afiliación:
Colombia
/
México
Institución/País de afiliación:
Fundación Médica Sur/MX
/
Instituto Nacional de Enfermedades Respiratorias Ismael Cosío Villegas/MX
/
La Sabana University/CO