In-Hospital Management and Long-term clinical outcomes and adherence in patients with acute decompensated heart failure: primary results of the first brazilian registry of heart failure (BREATHE)
J. card. fail
; ago.2023. graf
Artículo
en Inglés
| CONASS, Sec. Est. Saúde SP, SESSP-IDPCPROD, Sec. Est. Saúde SP
| ID: biblio-1509813
Biblioteca responsable:
BR79.1
ABSTRACT
BACKGROUND:
Heart failure (HF), a common cause of hospitalization, is associated with poor short-term clinical outcomes. Little is known about the long-term prognosis of patients with HF in Latin America.METHODS:
BREATHE was the first nationwide prospective observational study in Brazil that included patients hospitalized due to acute HF. Patients were included during 2 time periods February 2011-December 2012 and June 2016-July 2018. In-hospital management and 12-month clinical outcomes were assessed, and adherence to evidence-based therapies was evaluated.RESULTS:
A total of 3013 patients were enrolled at 71 centers in Brazil. At hospital admission, 83.8% had clear signs of pulmonary congestion. The main cause of decompensation was poor adherence to HF medications (27.8%). Among patients with reduced ejection fraction, concomitant use of beta-blockers, renin-angiotensin-aldosterone inhibitors, and spironolactone numerical decreased from 44.5% at hospital discharge to 35.2% at 3 months. The cumulative incidence of mortality at 12 months was 27.7%, with 24.3% readmission at 90 days and 44.4% at 12 months.CONCLUSIONS:
In this large national prospective registry of patients hospitalized with acute HF, rates of mortality and readmission were higher than those reported globally. Poor adherence to evidence-based therapies was common at hospital discharge and 12 months of follow-up.
Texto completo:
Disponible
Colección:
Bases de datos nacionales
/
Brasil
Contexto en salud:
ODS3 - Meta 3.4 Reducir las muertes prematuras por enfermedades no transmisibles
Problema de salud:
Enfermedad Cardiovascular
/
Otras Enfermedades Circulatorias
Base de datos:
CONASS
/
Sec. Est. Saúde SP
/
SESSP-IDPCPROD
Tipo de estudio:
Estudio observacional
/
Estudio pronóstico
País/Región como asunto:
America del Sur
/
Brasil
Idioma:
Inglés
Revista:
J. card. fail
Año:
2023
Tipo del documento:
Artículo
Institución/País de afiliación:
Centro de Pesquisa da Clínica Médica e Cardiologia da UNIFESP/BR
/
Clínica Gemelli/BR
/
Departamento de Insuficiência Cardíaca-DEIC-SBC/BR
/
Fundação Faculdade Regional de Medicina de São José do Rio Preto/BR
/
Hcor-Hospital do Coração/BR
/
Hospital Copa D'Or/BR
/
Hospital Naval Marcílio Dias/BR
/
Hospital Regional Hans Dieter Schmidt/BR
/
Hospital São Lucas-PUCRS/BR
/
Hospital Universidade Pedro Ernesto/BR