Severity of acute Zika virus infection: A prospective emergency room surveillance study during the 20152016 outbreak in Suriname
IDCases
; 10: 117-121, October 16, 2017. tab
Artículo
en Inglés
| MedCarib
| ID: biblio-906532
Biblioteca responsable:
TT5
ABSTRACT
Acute Zika virus (ZIKV) infection is usually mild and self-limiting. Earlier, we reported three cases of fatal acute ZIKV infection in patients without typical signs of ZIKV, but rather with criteria of systemic inflammation response syndrome (SIRS). To follow up these observations, we prospectively included patients at the emergency room with temperature instability and suspected to have acute ZIKV infection, SIRS, or both. A total of 102 patients were included of whom N =21 (21%) were suspected of acute ZIKV infection, N =56 (55%) of acute ZIKV infection with SIRS criteria, and N =25 (24%) of SIRS alone. ZIKV-PCR was positive in N =21 (20%) patients. Eight (38%) ZIKV-positive patients needed admission to the hospital of whom four (50%) presented with SIRS alone. One ZIKV-positive patient had vascular co-morbidity and died following shock and severe coagulopathy. We confirm the hypothesis that acute ZIKV infection can present atypical and severely with systemic inflammation and have lethal course particularly amongst patients with significant prior disease...(AU)
Texto completo:
Disponible
Colección:
Bases de datos internacionales
Base de datos:
MedCarib
Asunto principal:
Virus Zika
/
Infección por el Virus Zika
Tipo de estudio:
Estudio diagnóstico
/
Factores de riesgo
/
Estudio de tamizaje
Límite:
Femenino
/
Humanos
/
Masculino
País/Región como asunto:
America del Sur
/
Caribe Inglés
/
Surinam
Idioma:
Inglés
Revista:
IDCases
Año:
2017
Tipo del documento:
Artículo
Institución/País de afiliación:
Academic Hospital Paramaribo/SR
/
Erasmus University/NL
/
University of Groningen/NL