Estimated costs of hospitalization due to coronary artery disease attributable to familial hypercholesterolemia in the Brazilian public health system
Arch. endocrinol. metab. (Online)
; 62(3): 303-308, May-June 2018. tab
Artículo
en Inglés
| LILACS
| ID: biblio-950061
Biblioteca responsable:
BR1.1
ABSTRACT
ABSTRACT Objective: Cardiovascular diseases are the leading cause of death in Brazil, imposing substantial economic burden on the health care system. Familial hypercholesterolemia (FH) is known to greatly increase the risk of premature coronary artery disease (CAD). This study aimed to estimate the economic impact of hospitalizations due to CAD attributable to FH in the Brazilian Unified Health Care System (SUS). Subjects and methods: Retrospective, cross-sectional study of data obtained from the Hospital Information System of the SUS (SIHSUS). We selected all adults (≥ 20 years of age) hospitalized from 2012-2014 with primary diagnoses related to CAD (ICD-10 I20 to I25). Attributable risk methodology estimated the contribution of FH in the outcomes of interest, using international data for prevalence (0.4% and 0.73%) and relative risk for events (RR = 8.56). Results: Assuming an international prevalence of FH of 0.4% and 0.73%, of the 245,981 CAD admissions/year in Brazil, approximately 7,249 and 12,915, respectively, would be attributable to an underlying diagnosis of FH. The total cost due to CAD per year, considering both sexes and all adults, was R$ 985,919,064, of which R$ 29,053,500 and R$ 51,764,175, respectively, were estimated to be attributable to FH. The average cost per FH-related CAD event was R$ 4,008. Conclusion: Based on estimated costs of hospitalization for CAD, we estimated that 2.9-5.3% are directed to FH patients. FH can require early specific therapies to lower risk in families. It is mandatory to determine the prevalence of FH and institute appropriate treatment to minimize the clinical and economic impact of this disease in Brazil.
Texto completo:
Disponible
Colección:
Bases de datos internacionales
Contexto en salud:
Agenda de Salud Sostenible para las Américas
/
ODS3 - Salud y Bienestar
/
ODS3 - Meta 3.4 Reducir las muertes prematuras por enfermedades no transmisibles
Problema de salud:
Objetivo 4: Financiamiento de la salud
/
Objetivo 6: Sistemas de información para la salud
/
Meta 3.4: Reducir las muertes prematuras por enfermedades no transmisibles
/
Enfermedad Cardiovascular
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Enfermedades del Sistema Endocrino
/
Isquemia Miocárdica
Base de datos:
LILACS
Asunto principal:
Enfermedad de la Arteria Coronaria
/
Salud Pública
/
Costos de la Atención en Salud
/
Hospitalización
/
Hipercolesterolemia
Tipo de estudio:
Estudio de etiología
/
Evaluación económica en salud
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Estudio observacional
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Estudio de prevalencia
/
Factores de riesgo
Aspecto:
Determinantes sociales de la salud
/
Preferencia del paciente
Límite:
Adulto
/
Anciano
/
Femenino
/
Humanos
/
Masculino
País/Región como asunto:
America del Sur
/
Brasil
Idioma:
Inglés
Revista:
Arch. endocrinol. metab. (Online)
Asunto de la revista:
Endocrinologia
/
Metabolismo
Año:
2018
Tipo del documento:
Artículo
País de afiliación:
Brasil
Institución/País de afiliación:
Universidade Federal do Rio Grande do Sul/BR
/
Universidade de São Paulo/BR
/
Universidade do Estado do Rio de Janeiro/BR