Influence of tramadol on functional recovery of acute spinal cord injury in rats
Acta cir. bras
; 33(12): 1087-1094, Dec. 2018. tab, graf
Artículo
en Inglés
| LILACS
| ID: biblio-973483
Biblioteca responsable:
BR1.1
ABSTRACT
Abstract Purpose:
To evaluate the influence tramadol on functional recovery of acute spinal cord injury in rats.Methods:
Ten rats were divided into two groups (n = 5). All animals were submitted by a laminectomy and spinal cord injury at eighth thoracic vertebra. In control group, the rats didn't receive any analgesic. In tramadol group, the rats received tramadol 4mg/Kg at 12/12h until 5 days by subcutaneous. Animals were following by fourteen days. Was evaluated the Basso, Beattie, Bresnahan scale (locomotor evaluation) and Rat Grimace Scale (pain evaluation) at four periods.Results:
There no difference between the groups in locomotor evaluation in all periods evaluated (p>0.05) and in both groups there was a partial recover of function. The tramadol group show a lower pain levels at the first, third and seventh postoperatively days when comparing to the control group.Conclusion:
The tramadol as an analgesic agent don't influence on functional recovery of acute spinal cord injury in rats
Texto completo:
Disponible
Colección:
Bases de datos internacionales
Contexto en salud:
Agenda de Salud Sostenible para las Américas
Problema de salud:
Objetivo 9: Enfermedades no transmisibles y salud mental
Base de datos:
LILACS
Asunto principal:
Traumatismos de la Médula Espinal
/
Tramadol
/
Recuperación de la Función
/
Analgésicos Opioides
Tipo de estudio:
Estudio de evaluación
Límite:
Animales
Idioma:
Inglés
Revista:
Acta cir. bras
Asunto de la revista:
CIRURGIA GERAL
/
Procedimentos Cir£rgicos Operat¢rios
Año:
2018
Tipo del documento:
Artículo
País de afiliación:
Brasil
Institución/País de afiliación:
CESUPA/BR
/
Centro Universitário do Estado do Pará/BR
/
UEPA/BR
/
UFRA/BR
/
Universidade Federal Rural da Amazônia/BR
/
Universidade Federal do Pará/BR
/
Universidade do Estado do Pará/BR