Your browser doesn't support javascript.
loading
Expression of Osteopontin mRNA During Periodontal Healing Following Scaling and Root Planing
Mercia, Missy; Soeroso, Yuniarti; Lessang, Robert; Bachtiar, Boy Muchlis.
Afiliación
  • Mercia, Missy; s.af
  • Soeroso, Yuniarti; s.af
  • Lessang, Robert; s.af
  • Bachtiar, Boy Muchlis; s.af
Pesqui. bras. odontopediatria clín. integr ; 19(1): 4991, 01 Fevereiro 2019. tab, graf
Artículo en Inglés | LILACS, BBO - Odontología | ID: biblio-998272
Biblioteca responsable: BR1264.1
ABSTRACT

Objective:

To analyze osteopontin mRNA expression levels in subjects with periodontitis prior to (baseline) and 7, 14, and 28 days following scaling and root planing (SRP). Material and

Methods:

Gingival crevicular fluid was collected as clinical samples from four subjects with periodontitis (pocket depth, 4-5 mm) aged 35-54 years old as well as from three healthy subjects (controls). The osteopontin mRNA expression levels were measured by quantitative real-time polymerase chain reaction. Spearman's rank correlation between osteopontin levels in gingival crevicular fluid and the modified gingival index (MGI) was also performed.

Results:

The Wilcoxon signed-rank test showed no significant difference in osteopontin mRNA expression levels between baseline and 28 days following SRP (p=0.068). The Friedman test showed no significant difference in osteopontin mRNA expression levels between baseline and following SRP (7, 14, or 28 days) (p>0.05). Spearman's rank correlation showed no significant correlation between osteopontin mRNA expression levels and MGI (r=0.087; p=0.749).

Conclusion:

Following SRP of periodontal tissue, there was a decreasing trend in osteopontin mRNA expression; however, this finding was not statistically significant. Nevertheless, osteopontin can be used as a biomarker to monitor the healing process; however, further studies are required to clarify our results.
Asunto(s)


Texto completo: Disponible Colección: Bases de datos internacionales Base de datos: BBO - Odontología / LILACS Asunto principal: Periodontitis / ARN Mensajero / Aplanamiento de la Raíz / Osteopontina Tipo de estudio: Estudio de evaluación / Estudio observacional Límite: Adulto / Femenino / Humanos / Masculino País/Región como asunto: Asia Idioma: Inglés Revista: Pesqui. bras. odontopediatria clín. integr Asunto de la revista: Odontología Año: 2019 Tipo del documento: Artículo

Texto completo: Disponible Colección: Bases de datos internacionales Base de datos: BBO - Odontología / LILACS Asunto principal: Periodontitis / ARN Mensajero / Aplanamiento de la Raíz / Osteopontina Tipo de estudio: Estudio de evaluación / Estudio observacional Límite: Adulto / Femenino / Humanos / Masculino País/Región como asunto: Asia Idioma: Inglés Revista: Pesqui. bras. odontopediatria clín. integr Asunto de la revista: Odontología Año: 2019 Tipo del documento: Artículo
...