Genetic alterations in children and adolescents with acute myeloid leukaemia
Clin. transl. oncol. (Print)
; 12(9): 590-596, sept. 2010. ilus
Article
en Es
| IBECS
| ID: ibc-124303
Biblioteca responsable:
ES1.1
Ubicación: BNCS
ABSTRACT
Acute Myeloid Leukemia is a clinically and genetically heterogeneous disease, in which cytogenetic aberrations are the most important factors to determine biological behavior and prognosis. More than 20 different chromosomal abnormalities have been identified in a high percentage of children (70-85%) with the novo AML. We reviewed the most frequently found and the impact of these aberrations on prognosis. Differences according to the age of patients and mainly in relation to adult population have been enhanced, although the low incidence of AML in children and the high number of abnormalities make difficult to accurately define the prognosis significance of these aberrations (AU)
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Colección:
06-national
/
ES
Base de datos:
IBECS
Asunto principal:
Leucemia Mielomonocítica Aguda
/
Aberraciones Cromosómicas
/
Mutación
Tipo de estudio:
Prognostic_studies
Límite:
Adolescent
/
Child
/
Child, preschool
/
Female
/
Humans
/
Infant
/
Male
Idioma:
Es
Revista:
Clin. transl. oncol. (Print)
Año:
2010
Tipo del documento:
Article