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Lipodystrophies: adipose tissue disorders with severe metabolic implications
Cortés, Víctor A; Fernández-Galilea, Marta.
Afiliación
  • Cortés, Víctor A; Pontificia Universidad Católica de Chile. Department of Nutrition, Diabetes and Metabolism. Santiago. Chile
  • Fernández-Galilea, Marta; Pontificia Universidad Católica de Chile. Department of Nutrition, Diabetes and Metabolism. Santiago. Chile
J. physiol. biochem ; 71(3): 471-478, sept. 2015. tab
Article en En | IBECS | ID: ibc-142443
Biblioteca responsable: ES1.1
Ubicación: BNCS
ABSTRACT
Lipodystrophy encompass a group of heterogeneous disorders consisting in marked reduction, absence, and/or the redistribution of adipose tissue. Lipodystrophy is frequently complicated with severe insulin resistance, diabetes, hyperlipidemia, and fatty liver. Anatomically, lipodystrophies can be partial or generalized. Etiologically, they can be congenital or acquired. Lipodystrophy diagnosis can be challenging, and it has been suggested that partial forms can be easily misdiagnosed as common central obesity with associated metabolic syndrome. Conventional insulin-sensitizing approaches usually fail to fully ameliorate insulin resistance in lipodystrophic patients. Leptin replacement is an approved therapy for the metabolic complications of congenital generalized lipodystrophy. Novel nutritional interventions are promising complementary approaches for treating lipodystrophy metabolic complications
Asunto(s)
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Colección: 06-national / ES Base de datos: IBECS Asunto principal: Tejido Adiposo / Lipodistrofia / Enfermedades Metabólicas Límite: Humans Idioma: En Revista: J. physiol. biochem Año: 2015 Tipo del documento: Article
Buscar en Google
Colección: 06-national / ES Base de datos: IBECS Asunto principal: Tejido Adiposo / Lipodistrofia / Enfermedades Metabólicas Límite: Humans Idioma: En Revista: J. physiol. biochem Año: 2015 Tipo del documento: Article