Histopathological characterization of the oral lichenoid disease subtypes and the relation with the clinical data
Med. oral patol. oral cir. bucal (Internet)
; 22(3): e307-e313, mayo 2017. ilus, tab
Article
en En
| IBECS
| ID: ibc-163197
Biblioteca responsable:
ES1.1
Ubicación: BNCS
ABSTRACT
BACKGROUND: The aim of the study was to analyze the histopathological characteristics of samples with a diagnosis of oral lichenoid disease (OLD) and their link with the location and the type of clinical lesion, and the clinicopathological subtypes. MATERIAL AND METHODS: Retrospective study on 85 consecutive patients diagnosed with OLD (58 women and 27 men, mean age of 57.7 years). Clinical and histopathological characterization of each case (modified WHO criteria). Collection of the clinical and histopathological data of the lesions. Descriptive and comparative statistical analysis of the results. RESULTS: The 78.8% of the cases were considered clinically typical while the 21.2% were considered compatible. Histologically, 52.9% were classified as typical and 47.1% as compatible. Biopsies from 'plaque-like' lesions presented hyperkeratosis (p < 0.001) and epithelial dysplasia (p = 0.06) more frequently. Furthermore, acute inflammation was more evident in erosive-ulcerative lesions (p = 0.001). Differences regarding the location of the biopsy were statistically non-significant. However, 42.9% of the tongue biopsies showed epithelial dysplasia. CONCLUSIONS: The histopathological aspect of this disorder is not specific and does not allow us to differentiate between the main subtypes. Therefore, the main reasons to perform a biopsy in this disorder are to define the differential diagnosis and to rule out epithelial dysplasia or a carcinoma. The final histopathological result may be subject to the type of lesion that is biopsied
Texto completo:
1
Colección:
06-national
/
ES
Base de datos:
IBECS
Asunto principal:
Erupciones Liquenoides
/
Liquen Plano Oral
/
Hiperplasia Epitelial Focal
Tipo de estudio:
Observational_studies
Límite:
Humans
Idioma:
En
Revista:
Med. oral patol. oral cir. bucal (Internet)
Año:
2017
Tipo del documento:
Article