Hospital admission for symptoms exacerbation in 2.075 infants suffering from recurrent asthma-like symptoms: (EISL-3 South America)
Allergol. immunopatol
; 49(4): 47-54, jul. 2021. tab
Article
en En
| IBECS
| ID: ibc-214290
Biblioteca responsable:
ES1.1
Ubicación: ES15.1 - BNCS
ABSTRACT
Background: Contrary to what happens in children and adults, the prevalence and the factors related to hospitalisation for asthma/wheezing in infants with recurrent asthma-like symptoms are poorly known. Methods: This study is part of the International Study of Wheezing in infants Phase 3; 2,079 infants (aged 1218 months) with recurrent asthma-like symptoms, from 11 South American centres, were studied to determine the prevalence and the associated factors for wheezing exacerbation admission. Descriptive statistics and multivariate logistic regression were employed for analysis. Results: The prevalence of admission for wheezing was 29.7% (95% CI 27.731.6) and was significantly associated to severe wheezing episodes (OR: 3.89; 95% CI: 2.935.18, p < 0.001), physician-diagnosed asthma (OR: 1.79; 95% CI: 1.332.41, p < 0.0001), use of inhaled corticosteroids (OR: 1.78; 95%CI: 1.382.29, p < 0.0001), maternal tobacco smoking during pregnancy (OR: 1.69; 95% CI: 1.192.39, p = 0.003) and onset of wheezing in the first trimester of life (OR: 1.30; 95% CI: 1.021.66, p = 0.038). Breast feeding ≥4 months (OR: 0.72; 95% CI: 0.540.96, p = 0.004), maternal high educational level (>12 years) (OR: 0.66; 95% CI: 0.510.85, p = 0.001) and total monthly household income ≥US$ 3,000 (OR: 0.34; 95% CI: 0.180.67, p = 0.002), were protective factors. Conclusions: Infants with recurrent asthma-like symptoms have a high rate of admissions. Tobacco smoking in pregnancy, viral respiratory illness in the first trimester of life and severe progression were risks for admissions. Improving medical management to prevent severe exacerbations, prolonging the postnatal period at home longer than 3 months, favouring breastfeeding and avoiding smoking during pregnancy may have a preventive role for admissions in infants with recurrent asthma-like symptoms (AU)
Palabras clave
Texto completo:
1
Colección:
06-national
/
ES
Base de datos:
IBECS
Asunto principal:
Asma
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Brote de los Síntomas
Límite:
Female
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Humans
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Infant
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Male
País/Región como asunto:
America do sul
Idioma:
En
Revista:
Allergol. immunopatol
Año:
2021
Tipo del documento:
Article