Mean arterial pressure and the endothelin-1 levels in preeclampsia
Gac. sanit. (Barc., Ed. impr.)
; 35(supl. 2): S242-S244, 2021. tab
Article
en En
| IBECS
| ID: ibc-220949
Biblioteca responsable:
ES1.1
Ubicación: ES15.1 - BNCS
ABSTRACT
Objective:
This study aims to determine the correlation between Endothelin-1 levels and mean arterial pressure (MAP) with preeclampsia so that their combination can be used as the predictor of PE in early pregnancy.Method:
This study used a cross-sectional study with a case-control design carried out in February to June 2020 in several hospitals and health centers in Makassar city, namely Dr. Wahidin Soedirohusodo General Hospital, Hasanuddin University State University Hospital, health center Bara Baraya, health center Mamajang, and health center Antang. Respondents in this study were divided into 37 pregnant women with preeclampsia and 53 pregnant women with normotension. This study's criteria for respondents were 2035 years old, single pregnancy with > 20 weeks gestational. Data collected included education, body mass index (BMI), parity, the interval of pregnancy, and gestational age. ET-1 levels were determined using th ET-1 Elisa Kit with the ELISA method, and MAP was collected by measuring blood pressure when pregnant women came to health facilities.Results:
The mean serum ET-1 levels in the preeclampsia were highest than normotensive with a significant p-value of 0.001 (p < 0.05). The MAP in the preeclampsia was highest than normotensive too, with a significant value of p-value 0.001 (p < 0.05), and there is a positive correlation between ET-1 and MAP with r = 0.34 and p-value 0.001 (p < 0.05).Conclusion:
The combination of ET-1 and MAP can be considered as a prognostic factor to detect PE in early pregnancy. (AU)Palabras clave
Texto completo:
1
Colección:
06-national
/
ES
Base de datos:
IBECS
Asunto principal:
Preeclampsia
/
Endotelina-1
/
Presión Arterial
Límite:
Adult
/
Female
/
Humans
/
Pregnancy
Idioma:
En
Revista:
Gac. sanit. (Barc., Ed. impr.)
Año:
2021
Tipo del documento:
Article
/
Congress and conference