An overview on the relationship between residential radon and lung cancer: what we know and future research
Clin. transl. oncol. (Print)
; 25(12): 3357-3368, dec. 2023. mapas, tab
Article
en En
| IBECS
| ID: ibc-227282
Biblioteca responsable:
ES1.1
Ubicación: ES15.1 - BNCS
ABSTRACT
We aim to provide an overview of the research available on indoor radon and lung cancer, with a special focus on Spanish investigations. Early studies on underground miners established the link between radon and lung cancer, which was later confirmed for the general population by residential casecontrol studies. Spain contributed with extensive evidence, including 5 multicentric, hospital-based, casecontrol studies in the last 30 years, exploring diverse aspects, such as radon's effect on never-smokers, molecular pathways linking radon exposure to lung cancer risk, survival rates, mortality burden, and occupational exposure. There is a well-established causal association between radon with lung cancer. Despite pioneering research performed in our country by the Galician Radon Laboratory, particularly on driver genes, the evidence on the potential molecular pathways which makes radon a carcinogen is sparse. Also, relevant questions on the potential association of radon exposure with the induction of other diseases are still pending (AU)
Palabras clave
Texto completo:
1
Colección:
06-national
/
ES
Base de datos:
IBECS
Asunto principal:
Radón
/
Contaminación del Aire Interior
/
Neoplasias Pulmonares
/
Neoplasias Inducidas por Radiación
Límite:
Humans
Idioma:
En
Revista:
Clin. transl. oncol. (Print)
Año:
2023
Tipo del documento:
Article