Niveles plasmáticos de antitrombina III en hepatitis virales agudas / Antithrombin III levels in acute viral hepatitis

ABSTRACT

Aims.- concentration and activity of antitrombin are investigated in forty subjects. Matherial and methods.- Prospective study of 40 subjects (aged 36+/- 12 years). Twenty healthy subjects and twenty patients with acute hepatitis. Antithrombin III were determined by radial inmunodifusion (Mancini) – concentration- and cromogenic substrate – activity - . Results.- Plasma antithrombin III concentration and activity antithrombin III heparina cofactor by significantly increased in acute hepatitis compared with healthy subjects with statistical significance. Conclusion.- The antithrombin III (antigen and activity) present higher level in acute hepatitis than in healthy subjects like expression of a phenomenon of acute protein reaction (AU)