Intraoral epithelioid hemangioendothelioma: A case reportand review of the literature

ABSTRACT

The epithelioid hemangioendothelioma (EH) is an uncommon angiocentric neoplasm of borderline or intermediatemalignant potential, between the hemangioma and conventional angiosarcoma. It is characterized by the proliferationof endothelial cells with epithelioid or histiocitóide morphology with vacuolated cytoplasm and occasionaleosinophilic spindle cells. Shows potential for local recurrence as well as the ability to metastasize. Rarely affectsthe oral cavity, it have been described from 1975 until 2008 only 27 oral cases. Morphologically the EHs may beconfused with other lesions, from a hemangioma to a squamous cell carcinoma, and thus immunohistochemicalanalysis is required. This paper reports the clinical and immunohistochemical characteristics of a case of EH inthe gingiva of the tooth 35 of a 17 years-old-white-female. We present a review of the clinicopathological and immunohistochemicalcharacteristics of the intraoral epithelioid hemangioendothelioma cases previously reported (AU)