Aplicación de técnicas de biología molecular en la investigación médica en Chile / Molecular biology techniques in clinical research in Chile

RESUMO

Medical investigation in Chile is beginning to applymolecular biology methods as diagnostic tools and in studies establishing the prevalence of pathologies with Mendelian or multifactorial genetic origin. In this way,we are getting nearer to the strategies used worldwide for these purposes. Two studies published in this journal, 1 about hemophilia A where an analysis of intron-18 and intron-7 of the Factor VIII gene was applied as strategy for the diagnosis of carrier state in a Chilean population and the other one, about insulin-dependent diabetes mellitus in Santiago, Chile, with an analysis from immunogenetics to some environmental risk factors, constitute good examples about this integration