Imunodiagnóstico da esquistossomose mansônica com baixa carga parasitária / Immunodiagnosis of schistosomiasis mansonsi with light worm burden
Rev. Soc. Bras. Med. Trop
; 29(2): 145-52, Mar.-Apr. 1996. ilus, tab
Article
en Pt
| LILACS, SES-SP
| ID: lil-187141
Biblioteca responsable:
BR1.1
ABSTRACT
Presently, the schistosomiasis mansoni with low worm burden is frequent, thus immunologic assays of interest for the field diagnosis of Schistosoma mansoni light infections were evaluated here. Assays not assessed before (group I) and those requiring better validation (group II) for the screening of light infections were included in this study. In the group I, the immunofluorescence assays for the detection of IgM antibodies to worm antigens (IgM IFAw) and IgG antibodies to egg antigens (IgG IFAe) gave high levels of sensitivity, specificity, efficiency and predictive value of positive. However, the immunoenzymatic assays for the detection of IgM antibodies to worm antigens (IgM ELISAw) and to egg antigens (IgM ELISAe) had lower levels than the former assays. The assays from the group II designed mostly for the detection of IgG antibodies to same parasite antigens showed good diagnostic performance. The data obtained here contributed to evidenciate at least three category of immunoassays, and we concluded that those from the category I are suitable for seroepidemiologic purposes by keeping their diagnostic features unchanged even varying significantly the intensity of S. mansoni infection.
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Colección:
01-internacional
Base de datos:
LILACS
/
SES-SP
Asunto principal:
Schistosoma mansoni
/
Esquistosomiasis mansoni
/
Inmunoglobulina G
/
Inmunoglobulina M
/
Anticuerpos Antihelmínticos
/
Heces
Tipo de estudio:
Prognostic_studies
Límite:
Animals
/
Humans
Idioma:
Pt
Revista:
Rev. Soc. Bras. Med. Trop
Asunto de la revista:
MEDICINA TROPICAL
Año:
1996
Tipo del documento:
Article