New prevalence estimate of TT virus (TTV) infection in low- and high-risk population from Säo Paulo, Brazil
Rev. Inst. Med. Trop. Säo Paulo
; 44(4): 233-234, July-Aug. 2002. tab
Artículo
en Inglés
| LILACS, Sec. Est. Saúde SP
| ID: lil-321227
Biblioteca responsable:
BR1.1
ABSTRACT
The prevalence of TT virus (TTV) infection was investigated by Polymerase Chain Reaction (PCR) in low- (blood donors and healthy children/adolescents) and high-risk (hemophiliacs) groups from Säo Paulo, Brazil. Primers based on the untranslated region (UTR) of the viral genome proved to be much more ubiquitous, leading to much higher frequencies for both groups ( > or = 81 percent) than the earlier N22-PCR directed to the open reading frame 1 (blood donors, 5.5 percent, and hemophiliacs, 42.3 percent). The UTR-PCR also revealed an interesting profile for healthy children/adolescents very high prevalence at the early years and significant decrease in male teenagers. The N22-PCR, in turn, demonstrated higher frequency in hemophiliacs treated with fresh blood products (58 percent), than in those treated with virus-inactivated clotting factors (9.4 percent) and blood donors (5.5 percent)
Texto completo:
Disponible
Colección:
Bases de datos nacionales
/
Brasil
Base de datos:
LILACS
/
Sec. Est. Saúde SP
Asunto principal:
Torque teno virus
/
Infecciones por Virus ADN
Tipo de estudio:
Estudio de etiología
/
Estudio de prevalencia
/
Factores de riesgo
Límite:
Adolescente
/
Niño
/
Niño, preescolar
/
Femenino
/
Humanos
/
Masculino
País/Región como asunto:
America del Sur
/
Brasil
Idioma:
Inglés
Revista:
Rev. Inst. Med. Trop. Säo Paulo
Año:
2002
Tipo del documento:
Artículo
Institución/País de afiliación:
Fundaçäo Pró-Sangue Hemocentro de São Paulo/BR
/
Fundaçäo Pró-Sangue Hemocentro de Säo Paulo/BR
/
Institute of Infectology "Emílio Ribas"/BR
/
University of Säo Paulo/BR