Local anaesthetic medication for the treatment of asthma
Mem. Inst. Oswaldo Cruz
; 100(supl.1): 161-165, Mar. 2005.
Article
en En
| LILACS
| ID: lil-402193
Biblioteca responsable:
BR1.1
RESUMO
It is presumed that drugs able to prevent bronchial spasm and/or inflammation may have therapeutic potential to control asthma symptoms. The local anaesthetic lidocaine has recently received increased attention as an alternative form of treatment for asthmatic patients. This paper reviews the major findings on the topic and summarizes the putative mechanisms underlying the airway effects of local anaesthetic agents. We think that lidocaine extends the spectrum of options in asthma therapy, probably by counteracting both spasmogenic and inflammatory stimuli in the bronchial airways. The possibility of development of new anti-asthma compounds based on the synthesis of lidocaine derivatives is also on the horizon.
Texto completo:
1
Colección:
01-internacional
Base de datos:
LILACS
Asunto principal:
Asma
/
Antiasmáticos
/
Anestésicos Locales
/
Lidocaína
Límite:
Humans
Idioma:
En
Revista:
Mem. Inst. Oswaldo Cruz
Asunto de la revista:
MEDICINA TROPICAL
/
PARASITOLOGIA
Año:
2005
Tipo del documento:
Article
País de afiliación:
Brasil