Dosis de diálisis, nutrición y crecimiento en diálisis peritoneal pediátrica / Dialysis dose, nutrition and growth among pediatric patients on peritoneal dialysis
Rev. méd. Chile
; 133(12): 1455-1464, dic. 2005. ilus, tab
Article
en Es
| LILACS
| ID: lil-428529
Biblioteca responsable:
BR1.1
ABSTRACT
Stunting is common among pediatric patients on peritoneal dialysis. Aim:
To stablish the best profile for urea kinetic variables associated to growth inchildren on chronic peritoneal dialysis (PD). Patients andMethods:
Twenty patients, aged 1 month to 14 years, 13 males, were followed for 6-12 months, with monthly measurements of weight/age and height/age Z score; plasma creatinine, BUN, protein and albumin and urine and dialysate urea nitrogen, creatinine, protein and albumin. Minimum total Kt/V was 2.1. Dialysis dose (Kt/V), Protein Equivalent of Urea Nitrogen Appearence (PNA), Protein Catabolic Rate (PCR) and Nitrogen Balance (NB) were calculated. To identify the variable(s) associated to growth, the Tree Classification Model (CART) Enterprise Miner 8.1 was applied.Results:
Mean total/residual Kt/V 3.4±1.3/1.69±1.27; Daily Protein Intake (DPI) was 3.25±1.27 g/kg/day. nPNA, PCR and NB were 1.37±0.44, 0.84±0.33 and 1.86±1.25 g/kg/day, respectively. Mean heigth/age Z score was -2.3±1.19. Eleven patients showed a positive height/age delta Z (mean 0.55±0.38) and nine showed a negative growth (mean -0.50±0.42). The main variable explaining the positive growth was a Nitrogen Balance between 0.54 and 2.37 g/kg/ day, mean 1.55±0.21 (p <0.001). The second associated variable to growth was a residual Kt/V between 0.43 and 4.6 (2.02±0.49) (p <0.05). Kt/V and nPNA showed a significant correlation, but no correlation could be found between Kt/V and NB.Conclusions:
Nitrogen Balance was the main variable associated to growth in pediatric PD, with values between 0.53 to 2.38 g/kg/day. The second variable was a residual Kt/V between 0.43 and 4.6. Therapy should be reassessed with NB values less than 0.54 or above 2.37 g/kg/day....
Texto completo:
1
Colección:
01-internacional
Base de datos:
LILACS
Asunto principal:
Soluciones para Hemodiálisis
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Fenómenos Fisiológicos Nutricionales Infantiles
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Diálisis Peritoneal
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Crecimiento
Tipo de estudio:
Observational_studies
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Prognostic_studies
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Risk_factors_studies
Límite:
Adolescent
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Child
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Child, preschool
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Female
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Humans
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Infant
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Male
Idioma:
Es
Revista:
Rev. méd. Chile
Asunto de la revista:
MEDICINA
Año:
2005
Tipo del documento:
Article
/
Project document
País de afiliación:
Chile
Pais de publicación:
Chile