Uptake of macromolecules by cercariae during skin penetration and transformation to schistosomula (Schistosoma mansoni)
Mem. Inst. Oswaldo Cruz
; 105(4): 387-390, July 2010. ilus
Article
en En
| LILACS
| ID: lil-554802
Biblioteca responsable:
BR1.1
ABSTRACT
Here, we observed the uptake of membrane-impermeant molecules by cercariae as they penetrate the skin and are transformed into schistosomula. We propose that membrane-impermeant molecules, Lucifer Yellow, Propidium iodide and Hoechst 33258 enter the parasite through both thenephridiopore and the surface membrane and then diffuse throughout the body of the parasite. We present a hypothesis that the internal cells of the body of the schistosomulum represent a new host-parasite interface, at which skin-derived growth factors may stimulate receptors on internal membranes during transformation of the cercariae into the schistosomulum.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
LILACS
Asunto principal:
Schistosoma mansoni
/
Piel
/
Colorantes Fluorescentes
/
Interacciones Huésped-Parásitos
Límite:
Animals
Idioma:
En
Revista:
Mem. Inst. Oswaldo Cruz
Asunto de la revista:
MEDICINA TROPICAL
/
PARASITOLOGIA
Año:
2010
Tipo del documento:
Article
País de afiliación:
Brasil
/
Reino Unido