Anthocephalus cadamba (Roxb.) Miq., Rubiaceae, extract shows hypoglycemic effect and eases oxidative stress in alloxan-induced diabetic rats
Rev. bras. farmacogn
; 21(1)jan.-fev. 2011. ilus, tab
Article
en En
| LILACS
| ID: lil-580352
Biblioteca responsable:
BR1.1
ABSTRACT
The hydroethanolic extract of the flowering tops of Anthocephalus cadamba (Roxb.) Miq., Rubiaceae, a Bangladeshi medicinal plant, was studied for its potential hypoglycemic effect and antioxidant property in alloxan-induced diabetic rats. The extract induced significant reduction in serum glucose, and transaminases, e.g. aspartate transaminase (AST), alanine transaminase (ALT) and alkaline phosphatases (ALP), activities. Significant changes in the thiobarbituric acid reactive substances (TBARS), peroxidase and catalase levels during the experimental period were also observed. The results established that the hydroethanolic extract of the flowering tops of A. cadamba possesses hypoglycemic property and is able to protect liver and brain from oxidative damages caused by diabetes.
Texto completo:
1
Colección:
01-internacional
Base de datos:
LILACS
Idioma:
En
Revista:
Rev. bras. farmacogn
Asunto de la revista:
FARMACIA
Año:
2011
Tipo del documento:
Article
País de afiliación:
Bangladesh
/
Reino Unido
Pais de publicación:
Brasil