Enfermedad pulmonar obstructiva crónica: Mirada actual a una enfermedad emergente / Update on chronic obstructive pulmonary disease
Rev. méd. Chile
; 138(12): 1544-1552, dic. 2010. ilus
Artículo
en Español
| LILACS
| ID: lil-583053
Biblioteca responsable:
BR1.1
ABSTRACT
Chronic obstructive pulmonary disease (COPD), mainly caused by smoking, is predicted to be the third most frequent cause of death in the world by 2020. It is a multicomponent, progressive, disabling condition that ultimately ends in respiratory failure and death. There is evidence that systemic inflammation and extra pulmonary effects are also common in COPD, although the association between systemic inflammation and systemic manifestations of COPD is still not entirely clear. COPD is not only preventable but also treatable and the past decade has witnessed great progress in COPD research. New drugs have been developed and tested and a growing base of scientifc evidence now documents the efficacy of several therapies for symptoms and exacerbations. It is clear that many patients with the disease can beneft from an aggressive management, with a decrease in the frequency of hospitalizations and improvements in symptoms and quality of life. Moreover, basic and clinical scientists have now identifed cells, mechanisms, and molecules that play key roles in its pathogenesis. The advent of newer and more effective therapies will lead to a decline in the contribution of this disease to worldwide disease burden. COPD is now viewed under a new paradigm as preventable and treatable.
Texto completo:
Disponible
Colección:
Bases de datos internacionales
Contexto en salud:
ODS3 - Meta 3.4 Reducir las muertes prematuras por enfermedades no transmisibles
Problema de salud:
Enfermedad Pulmonar Obstructiva Crónica (EPOC)
/
Otras Enfermedades Respiratorias
Base de datos:
LILACS
Asunto principal:
Enfermedad Pulmonar Obstructiva Crónica
/
Inflamación
Tipo de estudio:
Estudio diagnóstico
/
Estudio pronóstico
Aspecto:
Preferencia del paciente
Límite:
Humanos
Idioma:
Español
Revista:
Rev. méd. Chile
Asunto de la revista:
Medicina
Año:
2010
Tipo del documento:
Artículo
País de afiliación:
Chile
Institución/País de afiliación:
Hospital Regional de Talca/CL