Aplicaciones de la toxina botulínica en glándulas salivales / Application of botulinum toxin in salivary glands
Rev. Hosp. Clin. Univ. Chile
; 22(4): 355-360, 2011.
Article
en Es
| LILACS
| ID: lil-647647
Biblioteca responsable:
CL36.1
ABSTRACT
Botulinum toxin is a neuromodulator produced by Clostridium botulinum, a gram-negative, anaerobic bacterium responsible for botulism. The clinical utility of botulinum toxin initially became evident in the treatment of strabismus. Subsequently, botulinum toxin has been used for a variety of other medical conditions such as muscular hyperactivity, including blepharospasm, hemifacial spasm, and cervical dystonia. In addition to its well-known applications, within the properties of botulinum toxin are those that make possible the treatment of various diseases affecting salivary glands and oral cavity. Recently there has been an important development in research and finding new applications in otolaryngology. Recent studies have demonstrated the advantages of botulinum toxin injected into the salivary glands of patients who present drooling, reducing the salivary flow and improving their quality of life. In the same way it has proven to be effective as a treatment of sialocele in patients with parotid gland surgery. In parotid and pharyngocutaneous fistula it has proven effective in reducing the salivary flow, facilitating the closure of the defect. Moreover, in patients with Freys syndrome it has been effective reducing symptoms and improving quality of life. It has also been histologically demonstrated its protective effect on the glandular damage in patients undergoing radiotherapy.
Texto completo:
1
Colección:
01-internacional
Base de datos:
LILACS
Asunto principal:
Glándulas Salivales
/
Toxinas Botulínicas
Aspecto:
Patient_preference
Límite:
Humans
Idioma:
Es
Revista:
Rev. Hosp. Clin. Univ. Chile
Asunto de la revista:
MEDICINA
Año:
2011
Tipo del documento:
Article
País de afiliación:
Chile