PAF-acether, superoxide anion and beta-glucurinidase as parameters of polymorphonuclear cell activation associated with cardiac surgery and cardiopulmonary bypass
Braz. j. med. biol. res
; 22(9): 1077-82, 1989. ilus
Article
en En
| LILACS
| ID: lil-83181
Biblioteca responsable:
BR26.1
RESUMO
Seven patients submitted to myocardial revascularization surgery with cardiopulmonary bypass were studied. Blood samples were obtained immediately before and 24 h after surgery. The parameters studied were the production of platelet activating factor (PAF-acether) and superoxide anion, cellular beta-glucuronidase activity as well as polymorphonuclear cell(PMN) and platelet count. Twenty-four h after surgery, there was a 54% decrease in platelet number (P<0.005), a 121% increase in PMN number (P<0.005), a 353% increase in PAF-acether (P<0.01), a 211% increase in superoxide anion (O2-) and a 104% increase in beta-glucuronidase (P<0.05) levels when compared with the pre-surgery levels. The present results indicate that PMN are more reactive after surgery with cardiopulmonary bypass
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Colección:
01-internacional
Base de datos:
LILACS
Asunto principal:
Factor de Activación Plaquetaria
/
Puente Cardiopulmonar
/
Superóxidos
/
Glucuronidasa
/
Revascularización Miocárdica
/
Neutrófilos
Tipo de estudio:
Risk_factors_studies
Límite:
Humans
Idioma:
En
Revista:
Braz. j. med. biol. res
Asunto de la revista:
BIOLOGIA
/
MEDICINA
Año:
1989
Tipo del documento:
Article
Pais de publicación:
Brasil