HIV-1 attachment: another look.
Trends Microbiol
; 7(4): 144-9, 1999 Apr.
Article
en En
| MEDLINE
| ID: mdl-10217828
ABSTRACT
HIV-1 attachment to host cells is generally considered to take place via high-affinity binding between CD4 and gp120. However, the binding of virion-associated gp120 to cellular CD4 is often weak, and most cell types that are permissive for HIV-1 infection express little CD4. Thus, other interactions between the virion and the cell surface could dominate the attachment process.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Proteína gp120 de Envoltorio del VIH
/
VIH-1
/
Receptores de Superficie Celular
Límite:
Humans
Idioma:
En
Revista:
Trends Microbiol
Asunto de la revista:
MICROBIOLOGIA
Año:
1999
Tipo del documento:
Article
País de afiliación:
Francia