Hypotensive, hypoglycaemic and toxicological studies on the flavonol C-glycoside shamimin from Bombax ceiba.
Planta Med
; 65(4): 331-4, 1999 May.
Article
en En
| MEDLINE
| ID: mdl-10364838
ABSTRACT
Shamimin, a C-flavonol glucoside from Bombax ceiba leaves showed significant potency as a hypotensive agent at the doses of 15 mg/kg, 3 mg/kg, 1 mg/kg and significant hypoglycaemic activity at 500 mg/kg in Sprague-Dawley rats. Further studies revealed that it did not cause any mortality in mice at the dose of 1 g/kg but in rats 500 mg/kg is a lethal dose. Aqueous and methanolic extracts of Bombax ceiba leaves and one of its fractions were also subjected to pharmacological and toxicological screening.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Plantas
/
Flavonoides
/
Glucosa
/
Hipoglucemiantes
/
Antihipertensivos
Límite:
Animals
Idioma:
En
Revista:
Planta Med
Año:
1999
Tipo del documento:
Article
País de afiliación:
Pakistán