Two new lignans from Lindera obtusiloba blume.
Arch Pharm Res
; 22(4): 417-22, 1999 Aug.
Article
en En
| MEDLINE
| ID: mdl-10489885
ABSTRACT
Two new furanolignans (3, 5), together with three known lignans (1, 2, 4), were isolated from the stem of Lindera obtusiloba (Lauraceae). The structures of the compounds were determined as actifolin (1), pluviatilol (2), 5,6-dihydroxymatairesinol (3), (+)-syringaresinol (4), and (+)-9'-O-trans-feruloyl-5,5'-dimethoxylariciresinol (5) on the basis of physicochemical and spectroscopic evidences. Compounds 1, 2, 3, and 5 showed cytotoxicity against a small panel of human tumor cell lines with ED50 values of 3.40 to approximately 19.27 microg/ml.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Plantas Medicinales
/
Lignanos
/
Antineoplásicos Fitogénicos
Límite:
Humans
País/Región como asunto:
Asia
Idioma:
En
Revista:
Arch Pharm Res
Año:
1999
Tipo del documento:
Article