Solid phase microextraction of alkenylbenzenes and other flavor-related compounds from tobacco for analysis by selected ion monitoring gas chromatography-mass spectrometry.
J Chromatogr A
; 858(1): 79-89, 1999 Oct 08.
Article
en En
| MEDLINE
| ID: mdl-10544893
ABSTRACT
Some constituents found in natural flavorings are known to exhibit toxic properties. We developed a rapid method for quantifying 12 flavor-related compounds in cigarette tobacco using headspace solid-phase microextraction coupled with gas chromatography-mass spectrometry. Using selected ion monitoring, we quantified and positively identified coumarin; pulegone; piperonal and nine alkenylbenzenes, including trans-anethole, safrole, methyleugenol and myristicin in one or more brands of cigarettes. In 62% of 68 brands analyzed, we detected one or more of the flavor-related compounds ranging from 0.0018 to 43 microg/g. Toxic properties of these flavor-related compounds may constitute an additional health risk related to cigarette smoking.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Plantas Tóxicas
/
Nicotiana
/
Derivados del Benceno
/
Cromatografía de Gases y Espectrometría de Masas
Tipo de estudio:
Diagnostic_studies
Idioma:
En
Revista:
J Chromatogr A
Año:
1999
Tipo del documento:
Article
País de afiliación:
Estados Unidos