Pharmacotechnical caracterization and effectiveness study of a dermopharmaceutical form: rosemary honey contributions as a moisturizing active.
Boll Chim Farm
; 138(8): 401-17, 1999 Sep.
Article
en En
| MEDLINE
| ID: mdl-10622106
ABSTRACT
We have designed, elaborated and studied a dermopharmaceutical form formulated on the basis of a modern self-emulsifying excipient and rosemary honey (known as Miel de La Alcarria--Spain--according to the Governing Council), in order to obtain a hight degree of cutaneous hydratation. The formulation is typified and characterized from a pharmacotechnical and rheological points of view. In this sense, the experimental protocol has emphasized rheological essays which give relevant practical information. Also, we have performed a complete study of it physical and structural stability, and, lastly, we evaluated the dermopharmaceutical effectiveness. The work plan included the following tests 1) Pharmacotechnical Essays--organoleptic characteristics, photomicrograh study, type of interposition, pH-determination, rheological and thixotropic study and physical stability tests; 2) Dermopharmaceutical Effectiveness Assays--Corneometric and Sebumetric measurements. From the results, we have deduced that the emulsified binary system that is proposed, stable from a physical and structural points of view, presents confirmed properties and a very good cosmetological adequation. In this sense, our emulsion presents a high degree of moisturizing/emollient power that qualifies it not only as a magnificent eudermic dermopharmaceutical form, but also as a very appropriate vehicle for Dermopharmaceutical and/or Dermatological Formulation.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Lamiaceae
/
Fármacos Dermatológicos
Tipo de estudio:
Guideline
Idioma:
En
Revista:
Boll Chim Farm
Año:
1999
Tipo del documento:
Article
País de afiliación:
España
Pais de publicación:
IT
/
ITALIA
/
ITALY
/
ITÁLIA