NF-kappa B modulates TNF-alpha production by alveolar macrophages in asymptomatic HIV-seropositive individuals.
J Immunol
; 164(3): 1588-94, 2000 Feb 01.
Article
en En
| MEDLINE
| ID: mdl-10640779
ABSTRACT
Local TNF-alpha production in different organs may affect HIV replication and pathogenesis. Alveolar macrophages (AMs) obtained by bronchoalveolar lavage from asymptomatic HIV-seropositive and HIV-seronegative individuals did not spontaneously release TNF-alpha, but LPS stimulation of these cells significantly increased TNF-alpha production. We tested whether NF-kappa B affects TNF-alpha production by AMs using N-tosyl-
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
FN-kappa B
/
Seropositividad para VIH
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Factor de Necrosis Tumoral alfa
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Macrófagos Alveolares
/
Proteínas I-kappa B
Tipo de estudio:
Observational_studies
Límite:
Adult
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Female
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Humans
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Male
/
Middle aged
Idioma:
En
Revista:
J Immunol
Año:
2000
Tipo del documento:
Article
País de afiliación:
Estados Unidos