New isomalabaricane triterpenes from the marine sponge Stelletta globostellata that induce morphological changes in rat fibroblasts.
J Nat Prod
; 63(2): 205-9, 2000 Feb.
Article
en En
| MEDLINE
| ID: mdl-10691710
ABSTRACT
Three new isomalabaricane triterpenes, 29-hydroxystelliferin D (2), 3-epi-29-hydroxystelliferin E (3), and 3-epi-29-hydroxystelliferin A (4), were isolated from the marine sponge Stelletta globostellata. Their structures, including absolute stereochemistry, were determined on the basis of spectral data and chemical methods. Rat fibroblasts treated with 0.2 microM of 2-4 exhibited unusual morphological characteristics, followed by death in 5 days.
Buscar en Google
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Poríferos
/
Triterpenos
/
Antineoplásicos
Límite:
Animals
Idioma:
En
Revista:
J Nat Prod
Año:
2000
Tipo del documento:
Article
País de afiliación:
Japón