Risk factors of mortality in perforated peptic ulcer.
Eur J Surg
; 166(2): 149-53, 2000 Feb.
Article
en En
| MEDLINE
| ID: mdl-10724493
ABSTRACT
OBJECTIVE:
To assess the risk factors that influence mortality from perforated peptic ulcer.DESIGN:
Retrospective study.SETTING:
General hospital, Taiwan.SUBJECTS:
179 patients who had their perforated peptic ulcers operated on and who had minimum follow-up of one year. MAIN OUTCOMEMEASURES:
Mortality.RESULTS:
The overall mortality was 15% (26/179). Of the 26 patients who died, the cause of death was uncontrolled systemic infection in 21 (81%), hypovolaemic shock in 2, and fatal arrhythmia and heart failure in 1 each. 15 of the patients who died of sepsis did not have fulminant abdominal sepsis. Most deaths occurred early after operation, (range 1-96 days). Old age, preoperative shock, and type of operation seemed to be related to these deaths on univariate analysis, but multivariate analysis showed that coexisting medical illness, delayed treatment, and low albumin concentration were independent risk factors for mortality.CONCLUSIONS:
To improve the result of treatment of perforated peptic ulcer, the diagnosis and treatment should not be delayed, the associated medical illnesses should be treated, and nutritional support should be given.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Úlcera Péptica Perforada
Tipo de estudio:
Etiology_studies
/
Observational_studies
/
Risk_factors_studies
Límite:
Adolescent
/
Adult
/
Aged
/
Aged80
/
Humans
/
Middle aged
Idioma:
En
Revista:
Eur J Surg
Año:
2000
Tipo del documento:
Article