[Experimental study of conjugates of a catabolite common to halothane, enflurane and fluroxene in guinea pigs]. / Etude expérimentale des conjugués d'un catabolite commun à l'halothane, enflurane et fluroxène chez le cobaye

ABSTRACT

The authors sensitized guinea pigs to a halothane catabolite, trifluoroacetic acid, combined with guinea pig albumin. They then exposed the animals to halothane. There was no correlation between the presence of humoral and cell-mediated immune reactions obtained with the catabolite and the incidence of liver necrosis.