Lympholeukemia in madai Pagrus major in Japan.
Dis Aquat Organ
; 40(2): 147-55, 2000 Mar 14.
Article
en En
| MEDLINE
| ID: mdl-10782349
ABSTRACT
Lympholeukemia has been occurring to an epizootic extent with mass mortality in 1 and 2 yr old madai (= Japanese red sea bream) Pagrus major in the winter season (October-May) in the western regions of Japan since 1975. Diseased fish displayed severe anemia and markedly increased numbers of neoplastic lymphocytoid and lymphoblastoid cells in the blood. Neoplastic cells originated in the splenic lymphatic cells and systemically caused severe metastatic lesions in the heart, liver, kidney, digestive tracts, gills and the lateral musculature. Electron microscopy revealed adeno-like viral particles (78 to 83 nm in diameter) in the nucleus of lymphoblastoid cells which appeared in the early prevalent stage but no viral particles in the lymphocytoid cells or plasmacytoid cells, which subsequently increased in number. In this paper, we describe light and electron microscopic features of neoplasms and neoplastic cells.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Leucemia Linfoide
/
Enfermedades de los Peces
Límite:
Animals
País/Región como asunto:
Asia
Idioma:
En
Revista:
Dis Aquat Organ
Asunto de la revista:
BIOLOGIA
/
MEDICINA VETERINARIA
/
MICROBIOLOGIA
Año:
2000
Tipo del documento:
Article
País de afiliación:
Japón