Murine models of inflammation: role of CD23.
Allergy
; 55 Suppl 61: 21-6, 2000.
Article
en En
| MEDLINE
| ID: mdl-10919501
The role of IgE in eosinophil recruitment and bronchial hyperresponsiveness has been extensively studied with murine models of inflammation. Many investigators using various knockout models have clearly shown that both IgE-dependent and -independent pathways play a role in eosinophil recruitment and bronchial hyperresponsiveness after allergen challenge, illustrating the complexity of airways inflammation. The expression of this response is likely to involve many interacting pathways, and it will be a considerable challenge to determine key points within these pathways that will yield novel targets for future therapeutic strategies.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Hiperreactividad Bronquial
/
Receptores de IgE
/
Inflamación
Límite:
Animals
Idioma:
En
Revista:
Allergy
Año:
2000
Tipo del documento:
Article
Pais de publicación:
Dinamarca