Activation of murine macrophage-like cells by granulocytin.
Biochem Biophys Res Commun
; 275(3): 850-3, 2000 Sep 07.
Article
en En
| MEDLINE
| ID: mdl-10973810
ABSTRACT
Granulocytin, a C-type lectin from Sarcophaga peregrina (flesh fly), stimulated glucose consumption and cytokine production by the mouse macrophage-like cell line J774.1. When J774.1 cells were pretreated with tunicamycin, their granulocytin-dependent TNF-alpha production was greatly reduced. These results suggest that the stimulus of granulocytin is transmitted to J774.1 cells via the carbohydrate chain of granulocytin receptors located on their surface.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Lectinas Tipo C
/
Dípteros
/
Lectinas
/
Activación de Macrófagos
/
Macrófagos
Límite:
Animals
Idioma:
En
Revista:
Biochem Biophys Res Commun
Año:
2000
Tipo del documento:
Article
País de afiliación:
Japón