Aspergillus terreus infections in haematological malignancies: molecular epidemiology suggests association with in-hospital plants.
J Hosp Infect
; 46(1): 31-5, 2000 Sep.
Article
en En
| MEDLINE
| ID: mdl-11023720
ABSTRACT
During a three-year period nine patients with haematological diseases after myeloablative chemotherapy died from invasive fungal infections caused by Aspergillus terreus. The hospital inanimate environment was monitored and A. terreus was cultured from potted plants in the vicinity of the patients. The patients (N = 14) and the environmental isolates (N = 2) were fingerprinted by RAPD-PCR with four different primers. Based on RAPD patterns the patients' isolates were differentiated into five different types; the environmental isolates represented two types. The isolates of four patients were identical to those found in the environment. Five additional patients were infected by RAPD types not found in the environment. One patient was infected with two different types. The data indicate a hospital-acquired infection in many of the patients and underline the need for careful environmental monitoring of units in which high-risk patients are housed.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Aspergilosis Broncopulmonar Alérgica
/
Aspergillus
/
Leucemia
/
Infección Hospitalaria
/
Brotes de Enfermedades
/
Hospitalización
/
Enfermedades Pulmonares Fúngicas
Tipo de estudio:
Risk_factors_studies
/
Screening_studies
Límite:
Humans
País/Región como asunto:
Europa
Idioma:
En
Revista:
J Hosp Infect
Año:
2000
Tipo del documento:
Article
País de afiliación:
Austria