Current perception thresholds of epileptic patients treated with valproate.
Seizure
; 9(7): 498-501, 2000 Oct.
Article
en En
| MEDLINE
| ID: mdl-11034875
ABSTRACT
We investigated the current perception threshold (CPT) of epileptic patients treated with valproate. The CPTs at frequencies of 5 Hz, 250 Hz and 2000 Hz in the control group of patients were 198.9 +/- 15.8, 62.0 +/- 18.9 and 35.3 +/- 15.8, respectively. The CPTs at 5 Hz, 250 Hz and 2000 Hz in the epileptic group of patients were 350.6 +/- 61.3, 338.6 +/- 64.3 and 193.2 +/- 21.1, respectively. The CPTs at 5 Hz, 250 Hz and 2000 Hz in the epileptic group were significantly higher than those of the control group. We measured the CPTs for 6 months after the administration of valproate in three patients with traumatic epilepsy. Their CPTs were higher than that of the epileptic group. The CPTs at 5 Hz, 250 Hz and 2000 Hz reached a maximum 4 weeks after the administration of valproate for two of these patients and in 6 weeks for the other patient. When the administration of valproate to a patient was stopped, CPTs decreased.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Ácido Valproico
/
Epilepsia Postraumática
/
Sistema Nervioso Periférico
/
Epilepsia
/
Anticonvulsivantes
Tipo de estudio:
Observational_studies
Límite:
Adolescent
/
Adult
/
Humans
Idioma:
En
Revista:
Seizure
Asunto de la revista:
NEUROLOGIA
Año:
2000
Tipo del documento:
Article
País de afiliación:
Japón