Comparison of two knowledge bases on the detection of drug-drug interactions.
Proc AMIA Symp
; : 171-5, 2000.
Article
en En
| MEDLINE
| ID: mdl-11079867
ABSTRACT
This paper describes a drug ordering decision support system that helps with the prevention of adverse drug events by detecting drug-drug interactions in drug orders. The architecture of the system was devised in order to facilitate its use attached to physician order entry systems. The described model focuses in issues related to knowledge base maintenance and integration with external systems. Finally, a retrospective study was performed. Two knowledge bases, developed by different academic centers, were used to detect drug-drug interactions in a dataset with 37,237 drug prescriptions. The study concludes that the proposed knowledge base architecture enables content from other knowledge sources to be easily transferred and adapted to its structure. The study also suggests a method that can be used on the evaluation and refinement of the content of drug knowledge bases.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Quimioterapia Asistida por Computador
/
Inteligencia Artificial
/
Interacciones Farmacológicas
Tipo de estudio:
Diagnostic_studies
/
Evaluation_studies
/
Observational_studies
/
Prognostic_studies
Límite:
Humans
Idioma:
En
Revista:
Proc AMIA Symp
Asunto de la revista:
INFORMATICA MEDICA
Año:
2000
Tipo del documento:
Article
País de afiliación:
Brasil