[Contribution of intracervical PGE2 administration in premature rupture of the membranes at term. Prospective randomised clinical trial]. / Apport de l'administration intracervicale de PGE2 dans les ruptures prématurées des membranes à terme. Essai clinique prospectif randomisé.
J Gynecol Obstet Biol Reprod (Paris)
; 29(6): 607-13, 2000 Oct.
Article
en Fr
| MEDLINE
| ID: mdl-11084468
ABSTRACT
OBJECTIVE:
To compare the clinical effectiveness and safety of intracervical dinoprostone versus conservative management of term prelabor rupture of membranes. SUBJECTS ANDMETHODS:
88 women with term prelabor rupture of membranes were assigned randomly to one of two groupsRESULTS:
44 women were allocated in each group. The means (+/- S. D) intervals from PROM to delivery and from inclusion to start of labour were significantly shorter in the dinoprostone group (19.5+/-6.2 vs 25.5+/-7.7 hours p<0.01 and 8.7+/-5.5 hours vs 14+/-6. 8; p=0.32 respectively). No significant differences were observed in the mean duration of labour (4.5+/-1.6 hours vs. 4.9+/-1.67 p=0.32). The rates of clinical amniotits were 15.9% in the dinoprostone group and 6.8% in the control group; difference is not statistically significant (p=0.17). The mode of delivery and Apgar score were similar in the two groups. Uterine tachysystole occurred more frequently in the dinoprostone group (6.8 vs 0%) but did not reach statistical significance.CONCLUSION:
Intracervical administration of dinoprostone with prelabor rupture of membrane at term and unripened cervix shortens the interval to delivery without a significant increase of maternal or neonatal morbidity.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Rotura Prematura de Membranas Fetales
/
Trabajo de Parto
/
Dinoprostona
/
Cuello del Útero
/
Edad Gestacional
Tipo de estudio:
Clinical_trials
/
Observational_studies
Límite:
Adult
/
Female
/
Humans
/
Newborn
/
Pregnancy
Idioma:
Fr
Revista:
J Gynecol Obstet Biol Reprod (Paris)
Año:
2000
Tipo del documento:
Article
País de afiliación:
Túnez