Immunity against Helicobacter pylori: significance of interleukin-4 receptor alpha chain status and gender of infected mice.
Infect Immun
; 69(1): 556-8, 2001 Jan.
Article
en En
| MEDLINE
| ID: mdl-11119552
ABSTRACT
Vaccination of interleukin-4 (IL-4) receptor alpha (IL-4Ralpha) chain-deficient BALB/c mice with Helicobacter pylori urease and cholera toxin or with urease-expressing, live attenuated Salmonella enterica serovar Typhimurium cells revealed that protection against H. pylori infection is independent of IL-4- or IL-13-mediated signals. A comparison of male and female mice suggests a sexual dimorphism in the extent of bacterial colonization that is particularly evident in the absence of the IL-4Ralpha chain.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Helicobacter pylori
/
Infecciones por Helicobacter
/
Receptores de Interleucina-4
Aspecto:
Determinantes_sociais_saude
Límite:
Animals
Idioma:
En
Revista:
Infect Immun
Año:
2001
Tipo del documento:
Article
País de afiliación:
Alemania