Stress-induced hormonal alterations.
Crit Care Clin
; 17(1): 1-10, 2001 Jan.
Article
en En
| MEDLINE
| ID: mdl-11219222
ABSTRACT
The hormonal alterations observed during critical illness are extremely diverse, being both adaptive and maladaptive. Central and peripheral mechanisms are at play depending on the duration and severity of the insult. Perturbations in the endocrine axes are exacerbated by endogenous mediators and by pharmacologic intervention. The emergence of the concept of the wound, or inflammatory lesion, as an endocrine organ introduces new potential mechanisms of stress physiology and possible interventional strategies. Whether the physiology of the wound can be manipulated to heighten organism resistance to stress either emergently or electively is theoretically appealing and supported by animal models. Currently, however, it remains a subject of ongoing controversy and research.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Estrés Fisiológico
/
Enfermedad Crítica
/
Sistemas Neurosecretores
Límite:
Humans
Idioma:
En
Revista:
Crit Care Clin
Asunto de la revista:
TERAPIA INTENSIVA
Año:
2001
Tipo del documento:
Article
País de afiliación:
Estados Unidos