[Histologic study of experimental spleen transplant in rats]. / Studio istologico del trapianto splenico sperimentale nei ratti.
Minerva Chir
; 55(11): 741-4, 2000 Nov.
Article
en It
| MEDLINE
| ID: mdl-11265146
ABSTRACT
BACKGROUND:
The objective of this paper was to demonstrate that the grafts of cervical splenic transplantation on rats using our experimental model present a normal histological appearance.METHODS:
Isogenic consanguineous Lewis rats 12 weeks old and weighing 250 gr. were used. Histological findings of a group of 25 cervical splenic grafts transplanted by means of splinting vascular venous microanastomoses and a group of 25 splenic grafts autotransplanted in the omentum were compared with a control group. The specimens were assigned according to a score of 0 to 4, following Moore's histological criteria.RESULTS:
All grafts in transplanted and autotransplanted groups had a score of 3 or 4. Then, all splenic grafts from the transplanted group had histological findings very similar to a normal spleen. In the autotransplantation group, the percentage of grafts with a score 3 (60%) was superior to the transplantation group (46%). However, the transplantation group presented a percentage of score 4 (54%), superior to the autotransplantation group (40%).CONCLUSIONS:
In our study all grafts from the cervical spleen transplantation group had histological findings very similar to a normal spleen. The percentage of spleens with histological normality in the transplantation group was superior to the autotransplantation group. However, there was no statistical significance.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Bazo
Tipo de estudio:
Prognostic_studies
Límite:
Animals
Idioma:
It
Revista:
Minerva Chir
Año:
2000
Tipo del documento:
Article
País de afiliación:
España