Anti-proliferative effect of two lactic acid bacteria strains of human origin on the growth of a myeloma cell line.
Lett Appl Microbiol
; 32(4): 287-92, 2001 Apr.
Article
en En
| MEDLINE
| ID: mdl-11298943
ABSTRACT
AIMS:
Twenty lactic acid bacteria strains were isolated from human faeces and tested by MTT assay for stimulation or inhibition of the proliferation of Vero and myeloma cells. METHODS ANDRESULTS:
None of the strains significantly affected the proliferation of Vero cells. However, two isolates (HN1 and HA8) showed a strong inhibition of myeloma cell proliferation (16.7 and 5.0%, respectively) by MTT assay.CONCLUSION:
Both strains have an anti-proliferative effect on a tumoral cell line. SIGNIFICANCE AND IMPACT OF THE STUDY The beneficial effect of LAB cancer therapy has been linked to their ability for immunomodulation.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Enterococcus faecium
/
Probióticos
/
Lactobacillus
/
Antineoplásicos
Límite:
Adult
/
Animals
/
Humans
/
Newborn
Idioma:
En
Revista:
Lett Appl Microbiol
Asunto de la revista:
MICROBIOLOGIA
Año:
2001
Tipo del documento:
Article
País de afiliación:
España